9.1 Proteins in Motion

Proteins in Motion (Module 9: The Optimizer). Key concept: Protein dynamics and flexibility. Explain why proteins are dynamic, and why that motion is functional rather than a defect.

• Explain why proteins are dynamic, and why that motion is functional rather than a defect
• Identify the hinge regions that permit large domain motions
• Distinguish an interpolation between two crystal structures from a simulation of the path between them
• Explain what molecular dynamics adds, and what its accessible timescales actually are