The Folding Architect

Capstone challenge for Module 3: The Architect. Identify helices, strands and loops in a 3D structure.

• Identify helices, strands and loops in a 3D structure
• Choose residues suited to each structural context
• Read a pLDDT profile as a measure of fold confidence, and recognise what it cannot tell you
• Explain how individual residue choices decide whether the protein folds at all