The Binder Generator

Capstone challenge for Module 8: The Creator. Evaluate binder designs against the published in-silico filters: interface PAE, binder pLDDT and RMSD to the design model.

• Evaluate binder designs against the published in-silico filters: interface PAE, binder pLDDT and RMSD to the design model
• Apply each filter to real output rather than accepting a summary metric
• Reach and defend the conclusion the evidence supports — including that none of the designs should go to the bench
• Integrate what Modules 3 to 8 taught into one evaluation