8.1 What Is De Novo Design?

What Is De Novo Design? (Module 8: The Creator). Key concept: Creating proteins with no evolutionary ancestor. Explain what de novo design means: a protein with no evolutionary ancestor.

• Explain what de novo design means: a protein with no evolutionary ancestor
• Survey what the field builds with it — binders, cages, enzymes and scaffolds
• Trace the line from Top7 to the SARS-CoV-2 miniprotein inhibitors
• Explain why binder design is the application this module follows