1.5 Aromatic Interactions

Aromatic Interactions (Module 1: The Building Blocks). Key concept: Pi stacking & cation-pi. Identify the three aromatic residues and their ring systems.

• Identify the three aromatic residues and their ring systems
• Explain what pi-electrons are and why aromatic rings attract each other
• Distinguish the two favourable stacking geometries, parallel-offset and T-shaped, from the unfavourable face-to-face one
• Build a stable aromatic arrangement by choosing the right orientation