# 9.1 Proteins in Motion

> Proteins in Motion (Module 9: The Optimizer). Key concept: Protein dynamics and flexibility. Explain why proteins are dynamic, and why that motion is functional rather than a defect.

Proteins in Motion (Module 9: The Optimizer). Key concept: Protein dynamics and flexibility. Explain why proteins are dynamic, and why that motion is functional rather than a defect.

- Explain why proteins are dynamic, and why that motion is functional rather than a defect
- Identify the hinge regions that permit large domain motions
- Distinguish an interpolation between two crystal structures from a simulation of the path between them
- Explain what molecular dynamics adds, and what its accessible timescales actually are

## Links

- [Module 9: The Optimizer](https://proteindesign.academy/module/9)
- [Introduction](https://proteindesign.academy/module/9/intro)
- [9.2 B-Factors and Flexibility](https://proteindesign.academy/module/9/2)
- [9.3 Structural Diagnostics](https://proteindesign.academy/module/9/3)
- [9.4 Energy Landscapes](https://proteindesign.academy/module/9/4)
- [9.5 Thermostability Engineering](https://proteindesign.academy/module/9/5)
- [9.integration The Guided Repair](https://proteindesign.academy/module/9/integration)
- [The Stability Optimizer](https://proteindesign.academy/module/9/capstone)
- [Use the Tools](https://proteindesign.academy/module/9/tools)