# 8.4 RFdiffusion: The Full Tool

> RFdiffusion: The Full Tool (Module 8: The Creator). Key concept: Full modular design pipeline. Walk the modular pipeline: target and hotspots → RFdiffusion → ProteinMPNN → AlphaFold-Multimer.

RFdiffusion: The Full Tool (Module 8: The Creator). Key concept: Full modular design pipeline. Walk the modular pipeline: target and hotspots → RFdiffusion → ProteinMPNN → AlphaFold-Multimer.

- Walk the modular pipeline: target and hotspots → RFdiffusion → ProteinMPNN → AlphaFold-Multimer
- Inspect generated backbones and compare them against each other
- Explain what the main RFdiffusion parameters control

## Links

- [Module 8: The Creator](https://proteindesign.academy/module/8)
- [Introduction](https://proteindesign.academy/module/8/intro)
- [8.1 What Is De Novo Design?](https://proteindesign.academy/module/8/1)
- [8.2 How Diffusion Models Work](https://proteindesign.academy/module/8/2)
- [8.3 Hotspot Definition](https://proteindesign.academy/module/8/3)
- [The Binder Generator](https://proteindesign.academy/module/8/capstone)
- [Use the Tools](https://proteindesign.academy/module/8/tools)