# 11.2 Target Selection

> Target Selection (Module 11: The Healer). Key concept: Targets must be disease-relevant and druggable. Interpret a structure in therapeutic context.

Target Selection (Module 11: The Healer). Key concept: Targets must be disease-relevant and druggable. Interpret a structure in therapeutic context.

- Interpret a structure in therapeutic context
- Characterise a protein–protein interface and identify its contact residues
- Select hotspot residues on conservation, exposure and spatial clustering together
- Explain why conservation measures what a pathogen has not yet changed, not what it cannot change — and what that means for a binder

## Links

- [Module 11: The Healer](https://proteindesign.academy/module/11)
- [Introduction](https://proteindesign.academy/module/11/intro)
- [11.1 Therapeutic Protein Design](https://proteindesign.academy/module/11/1)
- [11.3 De-immunization](https://proteindesign.academy/module/11/3)
- [11.4 Developability](https://proteindesign.academy/module/11/4)
- [11.integration The Drug Pipeline](https://proteindesign.academy/module/11/integration)
- [The Therapeutic Designer](https://proteindesign.academy/module/11/capstone)
- [Use the Tools](https://proteindesign.academy/module/11/tools)