# Module 11: The Healer

> Complete the full protein design pipeline for therapeutic applications.

Therapeutic Design

Complete the full protein design pipeline for therapeutic applications.

- Evaluate a disease target for druggability from structure and conservation data
- Select hotspot residues that are both constrained and clustered, knowing conservation buys time rather than permanence
- Find and remove T-cell epitopes without damaging the fold that carries them
- Navigate the trade-offs between stability, solubility, expressibility and immunogenicity
- Run the whole therapeutic pipeline, from target to a justified viability assessment

## Links

- [Introduction](https://proteindesign.academy/module/11/intro)
- [11.1 Therapeutic Protein Design](https://proteindesign.academy/module/11/1)
- [11.2 Target Selection](https://proteindesign.academy/module/11/2)
- [11.3 De-immunization](https://proteindesign.academy/module/11/3)
- [11.4 Developability](https://proteindesign.academy/module/11/4)
- [11.integration The Drug Pipeline](https://proteindesign.academy/module/11/integration)
- [The Therapeutic Designer](https://proteindesign.academy/module/11/capstone)
- [Use the Tools](https://proteindesign.academy/module/11/tools)
- [Start Here](https://proteindesign.academy/start-here)
- [Tools & Papers](https://proteindesign.academy/tools-and-papers)
- [Continuing Practice](https://proteindesign.academy/continuing-practice)