# The Peptide Engineer

> Capstone challenge for Module 1: The Building Blocks. Balance charge across a designed peptide to reach net neutrality.

Capstone challenge for Module 1: The Building Blocks. Balance charge across a designed peptide to reach net neutrality.

- Balance charge across a designed peptide to reach net neutrality
- Choose hydrophobic residues that give the core a stable centre
- Position charged pairs at salt-bridge distance
- Place aromatics in a stacking geometry that is actually favourable
- Satisfy all four constraints at once without introducing steric clashes

## Links

- [Module 1: The Building Blocks](https://proteindesign.academy/module/1)
- [Introduction](https://proteindesign.academy/module/1/intro)
- [1.1 The Hydrophobic Effect](https://proteindesign.academy/module/1/1)
- [1.2 Electrostatics & Salt Bridges](https://proteindesign.academy/module/1/2)
- [1.3 Size & Shape: The Packing Game](https://proteindesign.academy/module/1/3)
- [1.4 The Special Characters](https://proteindesign.academy/module/1/4)
- [1.5 Aromatic Interactions](https://proteindesign.academy/module/1/5)